Includes bibliographical references and index.

Introduction -- How can modeling and simulation help engineering of system of systems? -- Multidisciplinary, interdisciplinary and transdisciplinary federations in support of new medical simulation concepts: harmonics for the music of life -- Heterogeneous computing: an emerging paradigm of embedded systems design -- Numerical reproducibility of parallel and distributed stochastic simulation using high-performance computing.

Computational Frameworks: Systems, Models and Applications provides an overview of advanced perspectives that bridges the gap between frontline research and practical efforts. It is unique in showing the interdisciplinary nature of this area and the way in which it interacts with emerging technologies and techniques. As computational systems are a dominating part of daily lives and a required support for most of the engineering sciences, this book explores their usage in areas encompassing big data, high performance clusters, databases and information systems, integrated and embedded hardware/software components, smart devices, mobile and pervasive networks, and cyber physical systems.